“LX Technology(RELX)’s latest peer-reviewed study published in Journal of Applied Toxicology showed the cooling agent WS-23 widely used in e-cigarette has limited impact on the experiment animals at the tested dose. The study showed that there were no deaths in any of WS-23 treated groups in the acute and subacute inhalation studies, with no remarkable changes occurred in body weight, organ weight, hematology, and serum biochemistry, and no toxic effects in the histopathologic analysis. WS-23 is a well-known artificial synthesis cooling agent widely used in foods, medicines and tobaccos. As a commonly cooling agent in e-cigarette liquids, WS-23 has led to concerns about the inhalation toxicity with the prosperous of e-cigarettes in recent years. The study shows that at the tested dose level, inhalation of WS-23 will not bring toxic side effect to test animals.”
NOTE: We put forward the same caveat, as we would with negative ANTZ studies, that studies using rats does not mean the exact same results are always applicable in people.
ARTICLE LINK:
Latest Finding in Journal of Applied Toxicology on the Inhalation Safety Assessment of the Cooling agent WS-23 in E-Cigarette